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GSK-LSD1 dihydrochloride

CAT: 0013-GTR19173945-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173945-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK-LSD1 dihydrochloride is a potent and selective irreversible inhibitor of LSD1 (IC50 = 16 nM), demonstrating >1000-fold selectivity over related FAD-dependent enzymes like MAO-A/B. This inhibitor is a valuable chemical probe for investigating the role of LSD1 in epigenetic regulation, cancer biology, and other diseases in both cellular and animal models.
CAS Number
2102933-95-7
Product Name Alternative
Inhibit, LSD1, Inhibitor, Histone Demethylase, HistoneDemethylase, MAO, Monoamine Oxidase, GSK LSD1 dihydrochloride, GSK-LSD1, GSK-LSD1 (hydrochloride), GSK-LSD1 2HCl, GSKLSD1 dihydrochloride, GSK-LSD1 Dihydrochloride, GSK-LSD-1 dihydrochloride
Field of Research
Epigenetics & Chromatin, Metabolism Research, Neuroscience
Purity
98.72% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.91 mM) ; DMSO:25 mg/mL (86.43 mM) ; H2O:50 mg/mL (172.87 mM)
Smiles
Cl.Cl.C1[C@@H] (NC2CCNCC2) [C@@H]1c1ccccc1
Molecular Formula
C14H22Cl2N2
Molecular Weight
289.24
Storage Conditions
-20°C
Notes
For research use only.

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