Arginase 1 (Hepatocellular Carcinoma Marker) Mouse Monoclonal Antibody

• Gene Name:

  [ARG1]

• NCBI Gene ID:

  383

• Reactivity:

  Human; Others not known

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

• Other Gene Names:

  [ARG1; ARG1]

• Short Name:

  [Arginase 1]

• Other Product Names:

  [arginase-1 isoform 2; Arginase-1; arginase-1; arginase 1; Liver-type arginase; Type I arginase]

• NCBI GI Number:

  10947139

• NCBI Accession Number:

  NP_000036.2

• NCBI GB Accession Number:

  NM_000045.3

• Uniprot Accession Number:

  P05089

• CAS Number:

  9007-83-4