CD26 (DPP IV / ADA-Binding Protein) Mouse Monoclonal Antibody

CD26 (DPP IV / ADA-Binding Protein) Mouse Monoclonal Antibody

• CAS Number: 9007-83-4
• Gene Name: [DPP4]
• NCBI Gene ID: 1803
• Reactivity: Human, Rat.
  Does not react with Pig and Sheep.
  Others not tested
• Storage Conditions: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.
• Other Gene Names: [DPP4; DPP4; CD26; ADABP; ADCP2; DPPIV; TP103; ADCP2; CD26; ADCP-2; DPP IV]
• Short Name: [CD26]
• Other Product Names: [dipeptidyl peptidase 4; Dipeptidyl peptidase 4; dipeptidyl peptidase 4; dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2]
• NCBI GI Number: 18765694
• NCBI Accession Number: NP_001926.2
• NCBI GB Accession Number: NM_001935.3
• Uniprot Accession Number: P27487