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Prucalopride

CAT: 0013-GTR19173761-02Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173761-02Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prucalopride (R-93877) is a potent and selective agonist for the 5-HT4A and 5-HT4B receptors, exhibiting over 290-fold selectivity versus other 5-HT subtypes. It is widely used in gastrointestinal motility research, including in vitro receptor studies and in vivo models of colonic dysmotility and constipation.
CAS Number
179474-81-8
Product Name Alternative
Pseudo-intestinal obstruction, Prucalopride, Serotonin Receptor, R 93877, R-93877, R93877, chronic constipation, A427, A549, 5-HT Receptor, 5-HT4A, 5-HT4B, 5HTReceptor, 5HT Receptor, 5-hydroxytryptamine Receptor, Inhibitor, Lung cancer, inhibit
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery
Purity
99.99% (May vary between batches)
Solubility
DMSO:56 mg/mL (152.23 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:36 mg/mL (97.86 mM)
Smiles
COCCCN1CCC (CC1) NC (=O) c1cc (Cl) c (N) c2CCOc12
Molecular Formula
C18H26ClN3O3
Molecular Weight
367.87
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Prucalopride

Prucalopride is a member of benzamides.

CAS Number179474-81-8
PubChem CID3052762
IUPAC Name4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide
Molecular FormulaC18H26ClN3O3
Molecular Weight367.9
XLogP2
Topological Polar Surface Area76.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count25
Formal Charge0
Complexity445
SMILES
COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl
InChI
InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23)
InChIKey
ZPMNHBXQOOVQJL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Prucalopride
CAS: 179474-81-8
CID: 3052762
Formula: C18H26ClN3O3
MW: 367.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight367.9
XLogP32
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass367.1662694
Monoisotopic Mass367.1662694
Topological Polar Surface Area76.8 Ų
Heavy Atom Count25
Formal Charge0
Complexity445
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
S2875-01Prucalopride
CS-EO-02879Desmethyl Prucalopride
MBS3602709-01Prucalopride succinate
A11771-200Prucalopride 200mg

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