gp100/ Melanosome/ PMEL17/ SILV

• Gene Name:

  [SILV]

• NCBI Gene ID:

  6490

• Reactivity:

  Human, Horse.Does not react with rat, Others-not tested.

• Storage Conditions:

  Store at 2 to 8 °C. Antibody is stable for 24 months.

• Specificity:

  By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

• Other Gene Names:

  [PMEL; PMEL; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E; D12S53E; PMEL17; SILV; ME20M; ME20-S; ME20S]

• Short Name:

  [gp100]

• Other Product Names:

  [melanocyte protein PMEL isoform 2; Melanocyte protein PMEL; melanocyte protein PMEL; melanocyte protein mel 17; silver, mouse, homolog of; melanocyte protein Pmel 17; melanosomal matrix protein17; silver locus protein homolog; melanoma-associated ME20 antigen; melanocytes lineage-specific antigen GP100; premelanosome protein; ME20-M; ME20M; Melanocyte protein Pmel 17; Melanocytes lineage-specific antigen GP100; Melanoma-associated ME20 antigen; P1; P100; Premelanosome protein; Silver locus protein homologCleaved into the following 2 chains:M-alphaAlternative name(s):95 kDa melanocyte-specific secreted glycoprotein; P26; Secreted melanoma-associated ME20 antigen; ME20-S; ME20S]

• NCBI GI Number:

  318037593

• NCBI Accession Number:

  NP_001186982.1

• NCBI GB Accession Number:

  NM_001200053.1

• Uniprot Accession Number:

  P40967