Insulin-like Growth Factor-1 (IGF-1)

• Gene Name:

  [IGF1]

• NCBI Gene ID:

  3479

• Reactivity:

  Human, Mouse, Rat, Rabbit.

• Storage Conditions:

  Store at 2 to 8 °C. Antibody is stable for 24 months.

• Specificity:

  This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

• Other Gene Names:

  [IGF1; Igf1; IGFI; IGF-I; IGF1A; Igf-1; IGF-I]

• Short Name:

  [Insulin-like Growth Factor-1]

• Other Product Names:

  [insulin-like growth factor I isoform 4 preproprotein; Insulin-like growth factor I; insulin-like growth factor I; MGF; IGF-IA; IGF-IB; somatomedin-C; mechano growth factor; insulin-like growth factor IA; insulin-like growth factor IB; insulin-like growth factor 1 (somatomedin C); Somatomedin]

• NCBI GI Number:

  11024682

• NCBI Accession Number:

  NP_000609.1

• NCBI GB Accession Number:

  NM_000618.3

• Uniprot Accession Number:

  P05019