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CD34

CAT: 0544-MBS438348-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS438348-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[CD34]
NCBI Gene ID
947
Reactivity
Human, Cynomolgus Monkey, Rhesus Monkey. Does not react with rat, sheep, cow and dog.
Storage Conditions
Store at 2 to 8 °C. Antibody is stable for 24 months.
Specificity
This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified into three main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.
Other Gene Names
[CD34; CD34]
Short Name
[CD34]
Other Product Names
[hematopoietic progenitor cell antigen CD34 isoform a; Hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell antigen CD34; CD34 antigen; CD34 molecule; CD_antigen: CD34]
NCBI GI Number
68342038
NCBI Accession Number
NP_001020280.1
NCBI GB Accession Number
NM_001025109.1
Uniprot Accession Number
P28906

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244369CD34 (CD34 Molecule)
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033498CD34, ID (CD34, Hematopoietic progenitor cell antigen CD34, CD34)
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033498-FITCCD34, ID (CD34, Hematopoietic progenitor cell antigen CD34, CD34) (FITC)
244369-FITCCD34 (CD34 Molecule) (FITC)
244369-HRPCD34 (CD34 Molecule) (HRP)
244369-BiotinCD34 (CD34 Molecule) (Biotin)
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244369-PECD34 (CD34 Molecule) (PE)

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