Products for Research Use Only

Triparanol

CAT: 0013-GTR19173661-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173661-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Triparanol (NSC-65345) is a research compound that inhibits Hedgehog signaling by disrupting the post-translational modification of its ligands and the sterol-sensing domain of PTCH1. It has demonstrated antitumor activity in human models and functions as an antilipemic agent, though it is noted for significant ocular toxicity.
CAS Number
78-41-1
Product Name Alternative
Apoptosis, 24-DHCR, cholesterol biosynthesis, Hedgehog, Inhibitor, MER 29, MER29, MER-29, inhibit, NSC65345, NSC-65345, NSC 65345, Smoothened, PTCH1, Triparanol, tumor growth
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
99.72% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.28 mM) ; DMSO:50 mg/mL (114.16 mM)
Smiles
C (CC1=CC=C (Cl) C=C1) (O) (C2=CC=C (OCCN (CC) CC) C=C2) C3=CC=C (C) C=C3
Molecular Formula
C27H32ClNO2
Molecular Weight
438
Storage Conditions
-20°C
Notes
For research use only.