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Poziotinib

CAT: 0013-GTR19173660-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173660-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Poziotinib (NOV120101; HM781-36B) is an irreversible pan-HER inhibitor targeting EGFR (HER1), HER2, and HER4 with IC50 values of 3, 5, and 23 nM, respectively. It is a research tool used in vitro and in vivo to study oncogenic signaling and has been investigated in preclinical models of various cancers, including non-small cell lung cancer.
CAS Number
1092364-38-9
Product Name Alternative
NOV 120101, NOV120101, NOV-120101, EGFR, HM781-36B, HER1, HER2, HER4, Apoptosis, Poziotinib
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
97.81% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:91 mg/mL (185.21 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.72 mM)
Smiles
COc1cc2ncnc (Nc3ccc (Cl) c (Cl) c3F) c2cc1OC1CCN (CC1) C (=O) C=C
Molecular Formula
C23H21Cl2FN4O3
Molecular Weight
491.34
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-15730-01Poziotinib
A13044-100Poziotinib 100mg

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