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VU0071063

CAT: 0013-GTR19173655-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173655-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU0071063 is a small molecule activator of the Kir6.2/SUR1 pancreatic KATP channel complex. It is a valuable research tool for studying insulin secretion mechanisms and diabetes pathophysiology in both cellular and isolated tissue experimental models.
CAS Number
333415-38-6
Product Name Alternative
Specific, Potent, PotassiumChannel, Potassium Channel, VU 0071063, VU0071063, VU-0071063, inhibit, KcsA, Kir6.2/SUR1, Insulin, Inhibitor, Hyperpolarization, B-cell, Alzheimer
Field of Research
Pharmacology & Drug Discovery
Purity
99.33% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.13 mM) ; DMSO:50 mg/mL (153.19 mM)
Smiles
Cn1c2ncn (Cc3ccc (cc3) C (C) (C) C) c2c (=O) n (C) c1=O
Molecular Formula
C18H22N4O2
Molecular Weight
326.39
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

7-(4-(tert-butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

an activator of Kir6.2/SUR1; structure in first source

CAS Number333415-38-6
PubChem CID590142
IUPAC Name7-[(4-tert-butylphenyl)methyl]-1,3-dimethylpurine-2,6-dione
Molecular FormulaC18H22N4O2
Molecular Weight326.4
XLogP2.8
Topological Polar Surface Area58.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Heavy Atom Count24
Formal Charge0
Complexity508
SMILES
CC(C)(C)C1=CC=C(C=C1)CN2C=NC3=C2C(=O)N(C(=O)N3C)C
InChI
InChI=1S/C18H22N4O2/c1-18(2,3)13-8-6-12(7-9-13)10-22-11-19-15-14(22)16(23)21(5)17(24)20(15)4/h6-9,11H,10H2,1-5H3
InChIKey
ZFZAIHKQJBMYLO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-(4-(tert-butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
CAS: 333415-38-6
CID: 590142
Formula: C18H22N4O2
MW: 326.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight326.4
XLogP32.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass326.17427596
Monoisotopic Mass326.17427596
Topological Polar Surface Area58.4 Ų
Heavy Atom Count24
Formal Charge0
Complexity508
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA6900-10VU0071063

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