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GSK429286A

CAT: 0013-GTR19173654-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173654-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK429286A is a potent and selective ROCK1/2 inhibitor with IC50 values of 14 nM and 63 nM, respectively. It is widely used in research to investigate Rho/ROCK signaling pathways in cellular processes such as cytoskeletal regulation, and has been applied in both in vitro and in vivo models of neurological and cardiovascular function.
CAS Number
864082-47-3
Product Name Alternative
Inhibitor, inhibit, GSK429286A, GSK-429286A, ROCK, ROK, ROCK1, ROCK2, Rho-kinase, RHO 15, RHO15, RHO-15, Rho-associated kinase, Rho-associated protein kinase
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.68% (May vary between batches)
Solubility
Ethanol:4 mg/mL (9.25 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.63 mM) ; DMSO:140 mg/mL (323.8 mM)
Smiles
CC1=C (C (CC (=O) N1) c1ccc (cc1) C (F) (F) F) C (=O) Nc1cc2cn[nH]c2cc1F
Molecular Formula
C21H16F4N4O2
Molecular Weight
432.37
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
2637-5GSK429286A

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