CD1b

• Gene Name :

  [CD1B]

• NCBI Gene ID :

  910

• Reactivity :

  Human.

• Storage Conditions :

  Store at 2 to 8 °C. Antibody is stable for 24 months.

• Specificity :

  The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.

• Other Gene Names :

  [CD1B; CD1B; R1; CD1; CD1A]

• Short Name :

  [CD1b]

• Other Product Names :

  [T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1b; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; CD1b molecule; CD_antigen: CD1b]

• NCBI GI Number :

  4502645

• NCBI Accession Number :

  NP_001755.1

• NCBI GB Accession Number :

  NM_001764.2

• Uniprot Accession Number :

  P29016