Fibronectin

• Gene Name:

  [FN1]

• NCBI Gene ID:

  2335

• Reactivity:

  Human, Pig, Mouse, Rat. Others-not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C. . Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. It is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.

• Other Gene Names:

  [FN1; FN1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; FN; FN; CIG]

• Short Name:

  [Fibronectin]

• Other Product Names:

  [fibronectin isoform 3 preproprotein; Fibronectin; fibronectin; cold-insoluble globulin; migration-stimulating factor; fibronectin 1; Cold-insoluble globulin; CIG]

• NCBI GI Number:

  16933542

• NCBI Accession Number:

  NP_002017.1

• NCBI GB Accession Number:

  NM_002026.2

• Uniprot Accession Number:

  P02751