CD86

CAT: 0544-MBS438023-01Size: 0.5 mLDry Ice: NoHazardous: No
CAT#:0544-MBS438023-01Size:0.5 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[CD86]
NCBI Gene ID
942
Reactivity
Human, Mouse, Rat.
Storage Conditions
Store at 2 to 8 °C. Antibody is stable for 24 months.
Specificity
Recognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Other Gene Names
[CD86; CD86; B70; B7-2; B7.2; LAB72; CD28LG2; CD28LG2]
Short Name
[CD86]
Other Product Names
[T-lymphocyte activation antigen CD86 isoform 4; T-lymphocyte activation antigen CD86; T-lymphocyte activation antigen CD86; BU63; FUN-1; CTLA-4 counter-receptor B7.2; B-lymphocyte activation antigen B7-2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 molecule; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD_antigen: CD86]
NCBI GI Number
332634950
NCBI Accession Number
NP_001193853.1
NCBI GB Accession Number
NM_001206924.1
Uniprot Accession Number
P42081

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