EGFR

• Gene Name:

  [EGFR]

• NCBI Gene ID:

  1956

• Reactivity:

  Human.

• Storage Conditions:

  Store at 2 to 8 °C. Antibody is stable for 24 months.

• Specificity:

  This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

• Other Gene Names:

  [EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB; ERBB1; HER1]

• Short Name:

  [EGFR]

• Other Product Names:

  [epidermal growth factor receptor isoform a; Epidermal growth factor receptor; epidermal growth factor receptor; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1]

• NCBI GI Number:

  29725609

• NCBI Accession Number:

  NP_005219.2

• NCBI GB Accession Number:

  NM_005228.3

• Uniprot Accession Number:

  P00533