Products for Research Use Only
RegisterLogin

Suramin Sodium Salt

CAT: 0013-GTR19173979-04Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19173979-04Size:1 ml x 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Suramin Sodium Salt is a polysulphonated compound that inhibits tumor growth by blocking multiple growth factor receptors, including VEGF and PDGF, thereby suppressing angiogenesis and cell proliferation. It is widely used in oncology research, with applications in both in vitro studies of signaling pathways and in vivo models of cancer and parasitic diseases.
CAS Number
129-46-4
Product Name Alternative
Phosphatases, Phosphatase, Sirtuin, protein-tyrosine, Topoisomerase, Topo II, Suramin, Suramin hexasodium, Suramin hexasodium salt, Suramin Sodium Salt, SARS-CoV, SARSCoV, SARS coronavirus, Reverse Transcriptase, ReverseTranscriptase, PTPases, DNA, BAY 205, BAY205, BAY-205, anti-angiogenic, antitrypanosomal, antiparasitic, anti-neoplastic, Apoptosis, Inhibitor, NF060, NF-060, NF 060, Parasite, inhibit, IP5K
Field of Research
Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
97.47% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.4 mM) ; DMSO:252.5 mg/mL (176.68 mM)
Smiles
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].Cc1ccc (cc1NC (=O) c1cccc (NC (=O) Nc2cccc (c2) C (=O) Nc2cc (ccc2C) C (=O) Nc2ccc (c3cc (cc (c23) S ([O-]) (=O) =O) S ([O-]) (=O) =O) S ([O-]) (=O) =O) c1) C (=O) Nc1ccc (c2cc (cc (c12) S ([O-]) (=O) =O) S ([O-]) (=O) =O) S ([O-]) (=O) =O
Molecular Formula
C51H34N6Na6O23S6
Molecular Weight
1429.15
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Suramin Sodium

Suramin sodium is an organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness. It has a role as an antinematodal drug, an antineoplastic agent, a trypanocidal drug, an EC 2.7.11.13 (protein kinase C) inhibitor, a GABA-gated chloride channel antagonist, an angiogenesis inhibitor, a GABA antagonist, a ryanodine receptor agonist, an apoptosis inhibitor and a purinergic receptor P2 antagonist. It contains a suramin(6-).

CAS Number129-46-4
PubChem CID8514
IUPAC Namehexasodium;8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate
Molecular FormulaC51H34N6Na6O23S6
Molecular Weight1429.2
Topological Polar Surface Area551
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count23
Rotatable Bond Count10
Heavy Atom Count92
Formal Charge0
Complexity2940
SMILES
CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
InChI
InChI=1S/C51H40N6O23S6.6Na/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80;;;;;;/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80);;;;;;/q;6*+1/p-6
InChIKey
VAPNKLKDKUDFHK-UHFFFAOYSA-H
Chemical Structure
2D Structure
2D structure of Suramin Sodium
CAS: 129-46-4
CID: 8514
Formula: C51H34N6Na6O23S6
MW: 1429.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1429.2
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count23
Rotatable Bond Count10
Exact Mass1427.9385741
Monoisotopic Mass1427.9385741
Topological Polar Surface Area551 Ų
Heavy Atom Count92
Formal Charge0
Complexity2940
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count7
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19220524-01Suramin
GTR19156836-01Nigericin sodium salt
GTR19155266-01Resorufin sodium salt
GTR19155063-01DIDS sodium salt
GTR19154023-01Seladelpar sodium salt
GTR19177462-01Sulfaquinoxaline sodium salt
GTR19339140-01DIDS sodium salt
GTR19222621-01Cytostatin (sodium salt)
GTR19211160-01Brobactam Sodium Salt
GTR19206500Batimastat sodium salt

Alternative Products

CatalogName
GP0138-50mgSuramin sodium salt
HY-B0879A-01Suramin (sodium salt)
bs-75486C-01Suramin . sodium salt
AR-S11114-01Suramin-d12 Sodium Salt
HY-B0879AR-01Suramin (sodium salt) (Standard)
sc-507209FSuramin sodium

Popular Products