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Kobe2602

CAT: 0013-GTR19173150-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19173150-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kobe 2602 is a Ras inhibitor with demonstrated anticancer properties. It is used in cancer research to study Ras-driven signaling pathways and has been evaluated in both in vitro cell-based assays and in vivo tumor model studies.
CAS Number
454453-49-7
Product Name Alternative
H-Ras, inhibit, Inhibitor, Kobe 2602, Kobe2602, Kobe-2602, carcinoma, antiproliferative, Ras-Raf, Ras, Raf
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.36% (May vary between batches)
Solubility
DMSO:50 mg/mL (119.24 mM)
Smiles
[O-][N+] (=O) c1cc (cc (c1NNC (=S) Nc1ccc (F) cc1) [N+] ([O-]) =O) C (F) (F) F
Molecular Formula
C14H9F4N5O4S
Molecular Weight
419.31
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Kobe2602
CAS Number454453-49-7
PubChem CID3827738
IUPAC Name1-[2,6-dinitro-4-(trifluoromethyl)anilino]-3-(4-fluorophenyl)thiourea
Molecular FormulaC14H9F4N5O4S
Molecular Weight419.31
XLogP4.6
Topological Polar Surface Area160
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count3
Heavy Atom Count28
Formal Charge0
Complexity568
SMILES
C1=CC(=CC=C1NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])F
InChI
InChI=1S/C14H9F4N5O4S/c15-8-1-3-9(4-2-8)19-13(28)21-20-12-10(22(24)25)5-7(14(16,17)18)6-11(12)23(26)27/h1-6,20H,(H2,19,21,28)
InChIKey
NNPBSITXCGPXJC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Kobe2602
CAS: 454453-49-7
CID: 3827738
Formula: C14H9F4N5O4S
MW: 419.31
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight419.31
XLogP34.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count3
Exact Mass419.03113761
Monoisotopic Mass419.03113761
Topological Polar Surface Area160 Ų
Heavy Atom Count28
Formal Charge0
Complexity568
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19200132-01Kobe2601

Alternative Products

CatalogName
MBS3604539-01Kobe2602
A12578-50Kobe2602 50mg
A12578-250Kobe2602 250mg
A12578-25Kobe2602 25mg
A12578-100Kobe2602 100mg
A12578-10Kobe2602 10mg
A12578-10mM-DKobe2602 10mM * 1mL in DMSO

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