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Alpelisib

CAT: 0013-GTR19173088-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173088-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alpelisib (BYL-719) is an orally bioavailable, potent, and selective PI3Kα inhibitor (IC50=5 nM) with significantly lower activity against other PI3K isoforms. It demonstrates antitumor efficacy in both in vitro and in vivo models, specifically targeting cancers harboring PIK3CA mutations.
CAS Number
1217486-61-7
Product Name Alternative
Inhibitor, mutant, inhibit, metastasis, breast, antineoplastic, cancer, BYL 719, BYL719, BYL-719, Alpelisib, AKT, Phosphoinositide 3-kinase, PI3K, phosphorylation, PIK3CA, PI3Kα, p110α
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
Ethanol:2 mg/mL (4.53 mM) ; DMSO:240 mg/mL (543.64 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:8.2 mg/mL (18.57 mM)
Smiles
Cc1nc (NC (=O) N2CCC[C@H]2C (N) =O) sc1-c1ccnc (c1) C (C) (C) C (F) (F) F
Molecular Formula
C19H22F3N5O2S
Molecular Weight
441.47
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-15244-01Alpelisib
TRC-A382610-50MGAlpelisib (BYL719) M19 (Alpelisib metabolite)
CS-O-59033Alpelisib-d3
HY-15244A-01Alpelisib (hydrochloride)
MBS384426-01BYL719 (Alpelisib)
S2814-100mgAlpelisib (BYL719)
E8308-5mgAlpelisib hydrochloride
CS-O-59034Alpelisib-d6
CS-EO-02939Alpelisib D7
TRC-A963201-25MGAlpelisib-D7

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