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CGP 35348

CAT: 0013-GTR19172995-04Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172995-04Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGP 35348 is a selective GABAB receptor antagonist (EC50 = 34 μM) . It is utilized in neuroscience research to investigate mechanisms of synaptic transmission and has been applied in studies examining neuromuscular coordination and spatial learning deficits in murine models of neonatal brain injury.
CAS Number
123690-79-9
Product Name Alternative
Centrally, CGP35348, CGP-35348, CGP 35348, brain penetrant, active, Gamma-aminobutyric acid Receptor, GABAB, GABAReceptor, GABA Receptor, Inhibitor, inhibit, neuromuscular, neonatal damage, γ-Aminobutyric acid Receptor, spatial learning
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
≥98% (May vary between batches)
Solubility
DMSO:< 2.25 mg/mL (10 mM, insoluble or slightly soluble) ; H2O:41.66 mg/mL (184.97 mM)
Smiles
C (P (CCCN) (=O) O) (OCC) OCC
Molecular Formula
C8H20NO4P
Molecular Weight
225.22
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Cgp 35348

antagonizes both GABA-A and GABA-B receptors

CAS Number123690-79-9
PubChem CID107699
IUPAC Name3-aminopropyl(diethoxymethyl)phosphinic acid
Molecular FormulaC8H20NO4P
Molecular Weight225.22
XLogP-3.3
Topological Polar Surface Area81.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Heavy Atom Count14
Formal Charge0
Complexity182
SMILES
CCOC(OCC)P(=O)(CCCN)O
InChI
InChI=1S/C8H20NO4P/c1-3-12-8(13-4-2)14(10,11)7-5-6-9/h8H,3-7,9H2,1-2H3,(H,10,11)
InChIKey
QIIVUOWTHWIXFO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cgp 35348
CAS: 123690-79-9
CID: 107699
Formula: C8H20NO4P
MW: 225.22
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight225.22
XLogP3-3.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Exact Mass225.11299512
Monoisotopic Mass225.11299512
Topological Polar Surface Area81.8 Ų
Heavy Atom Count14
Formal Charge0
Complexity182
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS3616056-01CGP 35348
217271CGP 35348 (GABAB Receptor Antagonist, CGP 35348, CGP35348, CGP-35348)

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