Products for Research Use Only
RegisterLogin

MeBIO

CAT: 0013-GTR19172941-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19172941-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MeBIO is a small molecule aryl hydrocarbon receptor agonist that also inhibits GSK-3 and CDK1/CyclinB with IC50 values of 44 and 55 μM, respectively, while showing no effect on GSK-3β. It serves as a useful research tool for studying AhR signaling and cell cycle regulation in various in vitro biochemical and cellular assays.
CAS Number
667463-95-8
Product Name Alternative
Glycogen synthase kinase-3, Glycogen synthase kinase 3, GSK3, GSK-3, MeBIO, Inhibitor, inhibit, aryl hydrocarbon receptor, Aryl Hydrocarbon Receptor, Aryl Hydrocarbon Receptor (AhR), ArylHydrocarbonReceptor, Agonist, AhR, Cyclin dependent kinase, CDK5/p25, CDK, CDK1/CyclinB
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.84% (May vary between batches)
Solubility
DMSO:9 mg/mL (24.31 mM)
Smiles
CN1C (=O) \C (=C2/Nc3ccccc3/C/2=N\O) c2ccc (Br) cc12
Molecular Formula
C17H12BrN3O2
Molecular Weight
370.2
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

MeBIO
CAS Number667463-95-8
PubChem CID135524908
IUPAC Name6-bromo-1-methyl-3-(3-nitroso-1H-indol-2-yl)indol-2-ol
Molecular FormulaC17H12BrN3O2
Molecular Weight370.2
XLogP3.8
Topological Polar Surface Area70.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count23
Formal Charge0
Complexity465
SMILES
CN1C2=C(C=CC(=C2)Br)C(=C1O)C3=C(C4=CC=CC=C4N3)N=O
InChI
InChI=1S/C17H12BrN3O2/c1-21-13-8-9(18)6-7-11(13)14(17(21)22)16-15(20-23)10-4-2-3-5-12(10)19-16/h2-8,19,22H,1H3
InChIKey
PIDGGJYETVQYET-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of MeBIO
CAS: 667463-95-8
CID: 135524908
Formula: C17H12BrN3O2
MW: 370.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight370.2
XLogP33.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass369.01129
Monoisotopic Mass369.01129
Topological Polar Surface Area70.4 Ų
Heavy Atom Count23
Formal Charge0
Complexity465
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS3616080-01MeBIO
sc-221688GSK-3 Inhibitor IX, Control, MeBIO

Popular Products