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Fenamic acid

CAT: 0013-GTR19172790-02Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172790-02Size:100 mg
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Description
Fenamic acid (N-Phenylanthranilic acid) is a chloride channel-blocking scaffold for NSAIDs like mefenamic acid. It is used in pharmacological research to study ion channel function and inflammation, with studies in rats demonstrating its potential to induce renal papillary necrosis.
CAS Number
91-40-7
Product Name Alternative
Chloride Channel, chloride, Chloridechannel, Chloride channel, channel, Cl? Channels, derivant, Diphenylamine-2-carboxylic acid, blocker, antibacterial activity, analgesic activity, AKR1B10, 2- (Phenylamino) benzoic acid, 2-Anilinobenzoic acid, Inhibitor, IL-8, endocervical cells, Fenamic acid, orally active, inhibit, multidrug-resistant, NSAIA, N-Phenylanthranilic acid
Field of Research
Pharmacology & Drug Discovery
Purity
99.60% (May vary between batches)
Solubility
DMSO:55 mg/mL (257.94 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (18.76 mM)
Smiles
OC (=O) C1=C (NC2=CC=CC=C2) C=CC=C1
Molecular Formula
C13H11NO2
Molecular Weight
213.2319
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-Phenylanthranilic Acid

Fenamic acid is an aminobenzoic acid that is the N-phenyl derivative of anthranilic acid. It acts as a parent skeleton for the synthesis of several non-steroidal anti-inflammatory drugs. It has a role as a membrane transport modulator. It is an aminobenzoic acid and a secondary amino compound. It is functionally related to an anthranilic acid.

CAS Number91-40-7
PubChem CID4386
IUPAC Name2-anilinobenzoic acid
Molecular FormulaC13H11NO2
Molecular Weight213.23
XLogP4.4
Topological Polar Surface Area49.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Heavy Atom Count16
Formal Charge0
Complexity236
SMILES
C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)O
InChI
InChI=1S/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16)
InChIKey
ZWJINEZUASEZBH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-Phenylanthranilic Acid
CAS: 91-40-7
CID: 4386
Formula: C13H11NO2
MW: 213.23
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight213.23
XLogP34.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass213.078978594
Monoisotopic Mass213.078978594
Topological Polar Surface Area49.3 Ų
Heavy Atom Count16
Formal Charge0
Complexity236
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes