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GSK2578215A

CAT: 0013-GTR19172740-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172740-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK2578215A is a highly selective and potent inhibitor of LRRK2 kinase. This research compound is used in both in vitro and in vivo studies to investigate LRRK2's role in Parkinson's disease pathogenesis and related cellular pathways.
CAS Number
1285515-21-0
Product Name Alternative
LRRK2, LRRK2 (G2019S), LRRK2 (WT), Mitophagy, Mitochondrial Autophagy, inhibit, GSK2578215A, GSK-2578215A, Inhibitor, Leucine-rich repeat kinase 2, Autophagy
Field of Research
Cell Biology
Purity
97.93% (May vary between batches)
Solubility
DMSO:4.5 mg/mL (11.27 mM)
Smiles
Fc1cc (ccn1) -c1ccc (OCc2ccccc2) c (c1) C (=O) Nc1cccnc1
Molecular Formula
C24H18FN3O2
Molecular Weight
399.42
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-(benzyloxy)-5-(2-fluoropyridin-4-yl)-N-(pyridin-3-yl)benzamide
CAS Number1285515-21-0
PubChem CID68107965
IUPAC Name5-(2-fluoro-4-pyridinyl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide
Molecular FormulaC24H18FN3O2
Molecular Weight399.4
XLogP4.1
Topological Polar Surface Area64.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count30
Formal Charge0
Complexity543
SMILES
C1=CC=C(C=C1)COC2=C(C=C(C=C2)C3=CC(=NC=C3)F)C(=O)NC4=CN=CC=C4
InChI
InChI=1S/C24H18FN3O2/c25-23-14-19(10-12-27-23)18-8-9-22(30-16-17-5-2-1-3-6-17)21(13-18)24(29)28-20-7-4-11-26-15-20/h1-15H,16H2,(H,28,29)
InChIKey
WCIGMFCFPXZRMQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(benzyloxy)-5-(2-fluoropyridin-4-yl)-N-(pyridin-3-yl)benzamide
CAS: 1285515-21-0
CID: 68107965
Formula: C24H18FN3O2
MW: 399.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight399.4
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass399.13830499
Monoisotopic Mass399.13830499
Topological Polar Surface Area64.1 Ų
Heavy Atom Count30
Formal Charge0
Complexity543
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-13237-01GSK2578215A
A12798-50GSK2578215A 50mg
A12798-100GSK2578215A 100mg

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