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Serdemetan

CAT: 0013-GTR19172720-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172720-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Serdemetan (JNJ-26854165) is an orally active small molecule antagonist of HDM2, which disrupts the p53-HDM2 interaction to reactivate tumor suppression. It has demonstrated antineoplastic activity in preclinical in vitro and in vivo cancer models, supporting its investigation in oncology research.
CAS Number
881202-45-5
Product Name Alternative
E1 activating enzyme, E1 Enzyme, E1/E2/E3 Enzyme, E1Enzyme, E2 conjugating enzyme, E2 Enzyme, E2Enzyme, E3 Enzyme, Apoptosis, JNJ26854165, JNJ-26854165, JNJ 26854165, inhibit, p53, Inhibitor, HDM2, Mdm2, MDM-2/p53, E3 ligating enzyme, E3Enzyme, Ubiquitin activating enzyme, Ubiquitin conjugating enzyme, Ubiquitin ligase, Serdemetan
Field of Research
Cell Biology, Protein Biochemistry
Purity
97.13% (May vary between batches)
Solubility
DMSO:50 mg/mL (152.25 mM) ; Ethanol:2 mg/mL (6.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.09 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
C (Cc1c[nH]c2ccccc12) Nc1ccc (Nc2ccncc2) cc1
Molecular Formula
C21H20N4
Molecular Weight
328.41
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
BUP09761-01Serdemetan
A4204-100JNJ-26854165 (Serdemetan)
C16160-100mgSerdemetan (JNJ-26854165)

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