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SU5204

CAT: 0013-GTR19172719-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19172719-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SU5204 is a small molecule VEGFR2 (FLK-1) inhibitor with an IC50 of 4 μM, and it also inhibits HER2 (IC50 = 51.5 μM) . This SU5025 analogue is a useful research tool for studying angiogenesis and oncology in both cellular and animal models.
CAS Number
186611-11-0
Product Name Alternative
3-[ (2-Ethoxyphenyl) methylidene]-1H-indol-2-one, inhibit, EGFR, ErbB-1, Epidermal growth factor receptor, Inhibitor, HER1, HER2, SU 5204, SU5204, SU-5204, VEGFR, VEGFR2, Vascular endothelial growth factor receptor
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.46% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (103.65 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.54 mM)
Smiles
CCOc1ccccc1C=C1C (=O) Nc2ccccc12
Molecular Formula
C17H15NO2
Molecular Weight
265.31
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one
CAS Number186611-11-0
PubChem CID6509031
IUPAC Name(3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one
Molecular FormulaC17H15NO2
Molecular Weight265.31
XLogP3.2
Topological Polar Surface Area38.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Heavy Atom Count20
Formal Charge0
Complexity390
SMILES
CCOC1=CC=CC=C1/C=C\2/C3=CC=CC=C3NC2=O
InChI
InChI=1S/C17H15NO2/c1-2-20-16-10-6-3-7-12(16)11-14-13-8-4-5-9-15(13)18-17(14)19/h3-11H,2H2,1H3,(H,18,19)/b14-11-
InChIKey
MEZFKCPUSMBMAY-KAMYIIQDSA-N
Chemical Structure
2D Structure
2D structure of (3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one
CAS: 186611-11-0
CID: 6509031
Formula: C17H15NO2
MW: 265.31
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight265.31
XLogP33.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass265.110278721
Monoisotopic Mass265.110278721
Topological Polar Surface Area38.3 Ų
Heavy Atom Count20
Formal Charge0
Complexity390
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
BA6381-50SU5204
A22326-100SU5204 100mg
A22326-25SU5204 25mg
A22326-5SU5204 5mg
A22326-200SU5204 200mg
A22326-50SU5204 50mg
A22326-10SU5204 10mg
A22326-10mM-DSU5204 10mM * 1mL in DMSO

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