Products for Research Use Only

Tezacaftor

CAT: 0013-GTR19172654-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172654-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tezacaftor (VX-661) is a CFTR corrector small molecule used in research to investigate cystic fibrosis therapies. It facilitates the cellular processing and trafficking of mutant CFTR proteins, with applications in both in vitro biochemical assays and in vivo preclinical models of CFTR dysfunction.
CAS Number
1152311-62-0
Product Name Alternative
Inhibit, Inhibitor, Cystic fibrosis transmembrane conductance regulator, CFTR, Autophagy, Tezacaftor, VFTR, VX661, VX-661, VX 661
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.84% (May vary between batches)
Solubility
DMSO:245 mg/mL (470.7 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.61 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CC (C) (CO) c1cc2cc (NC (=O) C3 (CC3) c3ccc4OC (F) (F) Oc4c3) c (F) cc2n1C[C@@H] (O) CO
Molecular Formula
C26H27F3N2O6
Molecular Weight
520.5
Storage Conditions
-20°C
Notes
For research use only.

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