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DL-AP5

CAT: 0013-GTR19172617-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172617-01Size:5 mg
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Description
DL-AP5 is a racemic mixture that acts as a selective NMDA receptor antagonist. It is widely used in neuroscience research to study excitatory neurotransmission, synaptic plasticity, and mechanisms of epilepsy, with applications in both in vitro electrophysiology and in vivo models of convulsions.
CAS Number
76326-31-3
Product Name Alternative
Tonic pain, Retina, Inhibition, Ionotropic glutamate receptors, inhibit, NMDA, Ganglion cells, iGluR, Inhibitor, 2-APV, Antinociceptive activity, DL-AP5, DL-AP-5, DLAP5, DL AP5
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.33% (May vary between batches)
Solubility
DMSO:Insoluble; H2O:10 mM
Smiles
C (CC (C (O) =O) N) CP (=O) (O) O
Molecular Formula
C5H12NO5P
Molecular Weight
197.13
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-Amino-5-phosphonovaleric Acid

2-amino-5-phosphonopentanoic acid is the 5-phosphono derivative of 2-aminopentanoic acid; acts as an N-methyl-D-aspartate receptor antagonist. It has a role as a NMDA receptor antagonist. It is functionally related to a 2-aminopentanoic acid and a phosphonic acid.

CAS Number76326-31-3
PubChem CID1216
IUPAC Name2-amino-5-phosphonopentanoic acid
Molecular FormulaC5H12NO5P
Molecular Weight197.13
XLogP-5.3
Topological Polar Surface Area121
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count12
Formal Charge0
Complexity200
SMILES
C(CC(C(=O)O)N)CP(=O)(O)O
InChI
InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)
InChIKey
VOROEQBFPPIACJ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-Amino-5-phosphonovaleric Acid
CAS: 76326-31-3
CID: 1216
Formula: C5H12NO5P
MW: 197.13
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight197.13
XLogP3-5.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass197.04530948
Monoisotopic Mass197.04530948
Topological Polar Surface Area121 Ų
Heavy Atom Count12
Formal Charge0
Complexity200
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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