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Ceralasertib

CAT: 0013-GTR19173046-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173046-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ceralasertib (AZD6738) is a potent and selective orally active ATR kinase inhibitor with a reported IC50 of 1 nM. It demonstrates antitumor activity in preclinical research, being utilized in both in vitro and in vivo studies to investigate DNA damage response pathways and combination therapies in oncology.
CAS Number
1352226-88-0
Product Name Alternative
Ceralasertib, Ataxia telangiectasia mutated, ATM, ATM/ATR, ATM and RAD3 related, AZD 6738, AZD-6738, AZD6738, ATR, inhibit, Inhibitor
Field of Research
Molecular Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:7.6 mg/mL (18.42 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:39 mg/mL (94.54 mM) ; DMSO:250 mg/mL (606.05 mM)
Smiles
C[C@@H]1COCCN1c1cc (nc (n1) -c1ccnc2[nH]ccc12) C1 (CC1) S (C) (=N) =O
Molecular Formula
C20H24N6O2S
Molecular Weight
412.51
Storage Conditions
-20°C
Notes
For research use only.

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