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ELN-441958

CAT: 0013-GTR19172385-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172385-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ELN-441958 is a highly selective and potent neutral antagonist of the B1 receptor, exhibiting a Ki of 0.26 nM against the agonist [3H]DAKD in IMR-90 cell binding assays. This compound is a valuable research tool for investigating the distinct physiological and pathological roles of the B1 receptor in inflammation, pain, and sepsis using both in vitro and in vivo models.
CAS Number
913064-47-8
Product Name Alternative
B1 Receptor, anti-hyperalgesic, BradykininReceptor, Bradykinin Receptor, low CNS exposure, inhibit, Inhibitor, high oral bioavailability, ELN441958, ELN-441958, ELN 441958
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.90% (May vary between batches)
Solubility
DMSO:5.02 mg/mL (10.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2 mM)
Smiles
Clc1cccc2CN (C (=O) c12) c1cccc (c1) C (=O) N1CCC2 (CC1) CCN (CC2) c1ccncc1
Molecular Formula
C29H29ClN4O2
Molecular Weight
501.02
Storage Conditions
-20°C
Notes
For research use only.

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BUP07114-01ELN-441958
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A21207-100ELN-441958 100mg
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