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I-BET151

CAT: 0013-GTR19172308-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172308-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
I-BET151 (GSK1210151A) is a potent and selective small-molecule inhibitor of the BET bromodomain proteins BRD2, BRD3, and BRD4, with reported IC50 values of 0.5, 0.25, and 0.79 μM, respectively, in biochemical assays. It is widely used as a chemical probe in cancer, immunology, and inflammation research, demonstrating activity in both cellular studies and in vivo animal models of leukemia and myeloma.
CAS Number
1300031-49-5
Product Name Alternative
BRD3, BRD2, BRD4, BET, bromodomain, EpigeneticReaderDomain, Epigenetic Reader Domain, I BET151, I-BET 151, IBET151, I-BET151, I-BET-151, GSK1210151A, Inhibitor, inhibit
Field of Research
Epigenetics & Chromatin
Purity
97.34% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.81 mM) ; DMSO:50 mg/mL (120.35 mM)
Smiles
Cl.COc1cc2c3n ([C@H] (C) c4ccccn4) c (=O) [nH]c3cnc2cc1-c1c (C) noc1C
Molecular Formula
C23H21N5O3
Molecular Weight
415.44
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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HY-13235-01I-BET151
B1500-50I-BET151 (GSK1210151A)
T22845-01I-BET151 dihydrochloride
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