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Senicapoc

CAT: 0013-GTR19172200-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172200-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Senicapoc (ICA-17043) is a potent Gardos channel inhibitor with low nanomolar IC50 values, effectively preventing calcium-induced potassium efflux and red blood cell dehydration in vitro. It has demonstrated therapeutic potential in preclinical models for sickle cell disease by ameliorating RBC pathology.
CAS Number
289656-45-7
Product Name Alternative
KcsA, inhibit, Inhibitor, Gardos channel, ICA-17043, ICA17043, ICA 17043, PotassiumChannel, Potassium Channel, Senicapoc
Field of Research
Pharmacology & Drug Discovery
Purity
95.70% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.19 mM) ; DMSO:50 mg/mL (154.64 mM)
Smiles
NC (=O) C (c1ccccc1) (c1ccc (F) cc1) c1ccc (F) cc1
Molecular Formula
C20H15F2NO
Molecular Weight
323.34
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

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BA6866-10Senicapoc
CS-O-63473Senicapoc-d4
HY-50694R-01Senicapoc (Standard)
MBS386855-01Senicapoc (ICA-17043)
A11568-50Senicapoc (ICA-17043) 50mg
A11568-10Senicapoc (ICA-17043) 10mg
A11568-5Senicapoc (ICA-17043) 5mg
BS300121Senicapoc - Bio-X TM
A11568-200Senicapoc (ICA-17043) 200mg
A11568-100Senicapoc (ICA-17043) 100mg

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