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RG13022

CAT: 0013-GTR19172165-04Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172165-04Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RG13022 (Tyrphostin RG13022) is a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, exhibiting an IC50 of 4 μM against autophosphorylation. It is a valuable research tool for studying EGFR signaling pathways in cellular and biochemical assays.
CAS Number
136831-48-6
Product Name Alternative
HER1, EGFR, Epidermal growth factor receptor, ErbB-1, inhibit, Inhibitor, RG 13022, RG13022, RG-13022, Tyrphostin RG 13022, Tyrphostin RG13022, Tyrphostin RG-13022
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.38% (May vary between batches)
Solubility
DMSO:50 mg/mL (187.77 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.51 mM)
Smiles
COc1ccc (\C=C (\C#N) c2cccnc2) cc1OC
Molecular Formula
C16H14N2O2
Molecular Weight
266.29
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

RG 13022

3-(3,4-dimethoxyphenyl)-2-(3-pyridinyl)-2-propenenitrile is a dimethoxybenzene.

CAS Number136831-48-6
PubChem CID5468216
IUPAC Name(Z)-3-(3,4-dimethoxyphenyl)-2-pyridin-3-ylprop-2-enenitrile
Molecular FormulaC16H14N2O2
Molecular Weight266.29
XLogP2.6
Topological Polar Surface Area55.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count20
Formal Charge0
Complexity385
SMILES
COC1=C(C=C(C=C1)/C=C(\C#N)/C2=CN=CC=C2)OC
InChI
InChI=1S/C16H14N2O2/c1-19-15-6-5-12(9-16(15)20-2)8-14(10-17)13-4-3-7-18-11-13/h3-9,11H,1-2H3/b14-8+
InChIKey
DBGZNJVTHYFQJI-RIYZIHGNSA-N
Chemical Structure
2D Structure
2D structure of RG 13022
CAS: 136831-48-6
CID: 5468216
Formula: C16H14N2O2
MW: 266.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight266.29
XLogP32.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass266.105527694
Monoisotopic Mass266.105527694
Topological Polar Surface Area55.1 Ų
Heavy Atom Count20
Formal Charge0
Complexity385
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-101429-01RG13022
A20455-50RG13022 50mg
A20455-100RG13022 100mg
A20455-10RG13022 10mg
A20455-25RG13022 25mg
A20455-5RG13022 5mg
A20455-2RG13022 2mg
A20455-10mM-DRG13022 10mM * 1mL in DMSO

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