Products for Research Use Only

2,5-dimethyl Celecoxib

CAT: 0013-GTR19172141-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172141-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2,5-dimethyl Celecoxib is a celecoxib-based small molecule that selectively inhibits microsomal prostaglandin E synthase-1 (mPGES-1), a pivotal enzyme in inflammatory prostaglandin E2 biosynthesis. This inhibitor is utilized in research to investigate inflammation, pain, and cancer pathways in both cellular and animal models.
CAS Number
457639-26-8
Product Name Alternative
Beta-catenin, betacatenin, bcatenin, Apoptosis, 2,5 dimethyl Celecoxib, 2,5dimethyl Celecoxib, 2,5-dimethyl Celecoxib, Wnt, Wnt/betacatenin, Wnt/b-catenin, Wnt/β-catenin, PGE2, Prostaglandin Receptor, ProstaglandinReceptor, βcatenin
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.85% (May vary between batches)
Solubility
Ethanol:3 mg/mL (7.59 mM) ; DMSO:60 mg/mL (151.75 mM) ; DMF:5 mg/mL (12.65 mM) ; DMSO:PBS (pH 7.2) (1:3) :0.25 mg/mL (0.63 mM)
Smiles
CC1=CC (C2=CC (=NN2C2=CC=C (C=C2) S (N) (=O) =O) C (F) (F) F) =C (C) C=C1
Molecular Formula
C18H16F3N3O2S
Molecular Weight
395.4
Storage Conditions
-20°C
Notes
For research use only.