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AZD 6244

CAT: 0013-GTR19172064-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172064-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selumetinib is a potent, selective, and non-ATP-competitive MEK1/2 inhibitor (IC50=14 nM for MEK1) . It exhibits antitumor activity and is clinically used for neurofibromatosis type 1 (NF1) . This small molecule is widely applied in oncology research, including in vitro cell signaling studies and in vivo tumor model experiments.
CAS Number
606143-52-6
Product Name Alternative
ARRY-142886; Selumetinib
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
>98%
Bioactivity
ERK inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml)
Smiles
CN1C=NC2=C (F) C (NC3=CC=C (Br) C=C3Cl) =C (C=C12) C (=O) NOCCO
Molecular Formula
C17H15BrClFN4O3
Molecular Weight
457.68
Storage Conditions
-20°C
Notes
For research use only.

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