Products for Research Use Only

R428

CAT: 0013-GTR19172011-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172011-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bemcentinib (R428) is a potent and selective Axl kinase inhibitor with an IC50 of 14 nM. It has been studied in non-small cell lung cancer (NSCLC) research, demonstrating activity in both in vitro cellular assays and in vivo tumor models.
CAS Number
1037624-75-1
Product Name Alternative
Bemcentinib; BGB324
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
Potent and selective AXL inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
Nc1nc (Nc2ccc3CC[C@@H] (CCc3c2) N2CCCC2) nn1-c1cc2CCCc3ccccc3-c2nn1
Molecular Formula
C30H34N8
Molecular Weight
506.64
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1- (3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1 (15),2,4,6,11,13-hexaen-5-yl) -3-N-[ (7S) -7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine

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