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MLN4924

CAT: 0013-GTR19171947-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171947-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pevonedistat (MLN4924) is a selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 4.7 nM. It exhibits antitumor activity and has been investigated for treating myelodysplastic syndromes (MDS) in clinical research, supported by studies demonstrating its efficacy in both in vitro and in vivo cancer models.
CAS Number
905579-51-3
Product Name Alternative
Pevonedistat
Field of Research
Cell Biology, Molecular Biology, Neuroscience, Protein Biochemistry
Purity
>98%
Bioactivity
Nedd8 activating enzyme inhibitor
Form
Lyophilized
Solubility
Soluble in DMSO (up to 10 mg/ml) .
Smiles
N (C1=C2C (N (C=C2) [C@@H]3C[C@@H] (COS (N) (=O) =O) [C@@H] (O) C3) =NC=N1) [C@@H]4C=5C (CC4) =CC=CC5
Molecular Formula
C21H25N5O4S
Molecular Weight
443.53
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
((1S,2S,4R) -4- (4- (((S) -2,3-dihydro-1H-inden-1-yl) amino) -7H-pyrrolo[2,3-d]pyrimidin-7-yl) -2-hydroxycyclopentyl) methyl sulfamate

Alternative Products

CatalogName
B1036-5MLN4924
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A11260-5MLN4924 5mg
MBS386675-01MLN4924 (Pevonedistat)
A11260-50MLN4924 50mg
A11260-25MLN4924 25mg
A11260-10MLN4924 10mg

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