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AMG 900

CAT: 0013-GTR19171901-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171901-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMG 900 is a potent, selective pan-Aurora kinase inhibitor with IC50 values of 5, 4, and 1 nM for Aurora A, B, and C, respectively. It demonstrates over 10-fold selectivity against several other kinases. This compound has been utilized in preclinical research to investigate mitotic progression and has shown antitumor activity in various in vivo cancer models.
CAS Number
945595-80-2
Product Name Alternative
Aurora Kinase, Aurora C, AuroraKinase, Aurora A, Aurora B, AMG900, AMG-900, AMG 900, Inhibitor, inhibit, p38MAPK, p38α, p38 MAPK, Tyk2, TyrosineKinases, Tyrosine Kinases
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
≥98% (May vary between batches)
Solubility
DMSO:115 mg/mL (228.36 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.93 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;2% DMSO+40% PEG300+5% Tween 80+53% Saline:2 mg/mL (3.97 mM)
Smiles
Cc1csc (c1) -c1nnc (Nc2ccc (Oc3ncccc3-c3ccnc (N) n3) cc2) c2ccccc12
Molecular Formula
C28H21N7OS
Molecular Weight
503.58
Storage Conditions
-20°C
Notes
For research use only.

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