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Chromeceptin

CAT: 0013-GTR19171870-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19171870-02Size:1 ml x 10 mM (in DMSO)
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Description
Chromeceptin is a small molecule inhibitor of IGF signaling, reducing tumorsphere formation and suppressing the AKT/mTOR pathway. It is utilized in cancer research for in vitro studies of tumorigenesis and stemness, and has been investigated in vivo for its potential anti-tumor effects.
CAS Number
331859-86-0
Product Name Alternative
Chromeceptin, Akt, 2-amino-7- (dimethylamino) -4-[3- (trifluoromethyl) phenyl]-4H-chromene-3-carbonitrile, IGF1R, IGF-1R, mTOR
Field of Research
Signal Transduction
Purity
99.72% (May vary between batches)
Solubility
DMSO:90 mg/mL (250.45 mM)
Smiles
CN (C) c1ccc2C (C (C#N) =C (N) Oc2c1) c1cccc (c1) C (F) (F) F
Molecular Formula
C19H16F3N3O
Molecular Weight
359.35
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Chromeceptin

inhibits Igf2 at the transcriptional level; structure in first source

CAS Number331859-86-0
PubChem CID3113922
IUPAC Name2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile
Molecular FormulaC19H16F3N3O
Molecular Weight359.3
XLogP4.3
Topological Polar Surface Area62.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Heavy Atom Count26
Formal Charge0
Complexity607
SMILES
CN(C)C1=CC2=C(C=C1)C(C(=C(O2)N)C#N)C3=CC(=CC=C3)C(F)(F)F
InChI
InChI=1S/C19H16F3N3O/c1-25(2)13-6-7-14-16(9-13)26-18(24)15(10-23)17(14)11-4-3-5-12(8-11)19(20,21)22/h3-9,17H,24H2,1-2H3
InChIKey
GVINXTXGDDSXFQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Chromeceptin
CAS: 331859-86-0
CID: 3113922
Formula: C19H16F3N3O
MW: 359.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight359.3
XLogP34.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass359.12454663
Monoisotopic Mass359.12454663
Topological Polar Surface Area62.3 Ų
Heavy Atom Count26
Formal Charge0
Complexity607
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-115449-01Chromeceptin

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