Products for Research Use Only

Volasertib

CAT: 0013-GTR19171822-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171822-01Size:5 mg
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Description
Volasertib (BI 6727) is a highly potent and selective PLK1 inhibitor (IC50: 0.87 nM) with additional activity against PLK2 and PLK3. It promotes mitotic arrest and apoptosis in cancer cells and has demonstrated antitumor efficacy in various preclinical in vitro and in vivo models, supporting its investigation in oncology research.
CAS Number
755038-65-4
Product Name Alternative
BI 6727
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Potent and selective inhibitor of Polo-like Kinase 1
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
CC[C@H]1N (C (C) C) c2nc (Nc3ccc (cc3OC) C (=O) N[C@H]3CC[C@@H] (CC3) N3CCN (CC4CC4) CC3) ncc2N (C) C1=O
Molecular Formula
C34H50N8O3
Molecular Weight
618.82
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[4-[4- (Cyclopropylmethyl) piperazin-1-yl]cyclohexyl]-4-[[ (7R) -7-ethyl-5-methyl-6-oxo-8-propan-2-yl-7H-pteridin-2-yl]amino]-3-methoxybenzamide

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