Products for Research Use Only

GSK1324726A

CAT: 0013-GTR19171820-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171820-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK1324726A (I-BET726) is a potent and selective BET bromodomain inhibitor, exhibiting IC50 values of 41 nM, 31 nM, and 22 nM for BRD2, BRD3, and BRD4, respectively. This tool compound is widely used in vitro and in vivo to investigate BET protein function in oncology, immunology, and inflammatory disease research.
CAS Number
1300031-52-0
Product Name Alternative
BRD2, BRD3, BRD4, Apoptosis, inhibit, Inhibitor, I-BET 726, I-BET726, I-BET-726, GSK1324726A, GSK-1324726A, Epigenetic Reader Domain, EpigeneticReaderDomain
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
98.34% (May vary between batches)
Solubility
DMSO:50 mg/mL (114.97 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.6 mM) ; Ethanol:80 mg/mL (183.95 mM)
Smiles
C (C) (=O) N1C=2C ([C@H] (NC3=CC=C (Cl) C=C3) C[C@@H]1C) =CC (=CC2) C4=CC=C (C (O) =O) C=C4
Molecular Formula
C25H23ClN2O3
Molecular Weight
434.91
Storage Conditions
-20°C
Notes
For research use only.

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