Zotarolimus

CAT: 0013-GTR19171808-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19171808-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Zotarolimus (ABT-578) is a rapamycin analog that potently inhibits FKBP-12 with an IC50 of 2.8 nM. It is widely used in cardiovascular and oncology research to study mTOR pathway inhibition in both cellular assays and animal models of restenosis and cancer.

CAS Number

221877-54-9

Product Name Alternative

Rapamycin, stents, restenosis, Zotarolimus, coronary, disease, drug-eluting, A 179578, A179578, A-179578, ABT578, ABT-578, ABT 578, artery, inhibit, immunosuppressant, FKBP-12, Inhibitor

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

95.00% (May vary between batches)

Solubility

DMSO:93 mg/mL (96.25 mM) ; Ethanol:93 mg/mL (96.25 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (3.42 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

[H][C@@]12CC[C@@H] (C) [C@@] (O) (O1) C (=O) C (=O) N1CCCC[C@@]1 ([H]) C (=O) O[C@@] ([H]) (CC (=O) [C@H] (C) \C=C (C) \[C@@H] (O) [C@@H] (OC) C (=O) [C@H] (C) C[C@H] (C) \C=C\C=C\C=C (C) \[C@H] (C2) OC) [C@H] (C) C[C@@H]1CC[C@H] ([C@@H] (C1) OC) n1cnnn1

Molecular Formula

C52H79N5O12

Molecular Weight

966.21

Storage Conditions

-20°C

Notes

For research use only.

Alternative Products

Catalog	Name
T6033-01	Zotarolimus
A11950-2	Zotarolimus 2mg
sc-220423	Zotarolimus-d3
A11950-5	Zotarolimus 5mg
A11950-50	Zotarolimus 50mg
A11950-1	Zotarolimus 1mg
Z700800	Zotarolimus, >90%
A11950-100	Zotarolimus 100mg
A11950-25	Zotarolimus 25mg
A11950-10	Zotarolimus 10mg

Zotarolimus

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