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Mubritinib

CAT: 0013-GTR19171721-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171721-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mubritinib (TAK-165) is a potent and selective small molecule inhibitor targeting the HER2/ErbB2 tyrosine kinase, demonstrating an IC50 of 6 nM. It has been utilized in preclinical research to investigate HER2-driven cancers, showing antitumor activity in both cellular assays and in vivo xenograft models.
CAS Number
366017-09-6
Product Name Alternative
PDGFR, JAK1, inhibit, Mubritinib, Inhibitor, HER2/ErbB2, HER1, ErbB-1, Epidermal growth factor receptor, EGFR, FGFR, TAK165, TAK-165, TAK 165
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.61% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (4.27 mM) ; DMSO:35.1 mg/mL (74.92 mM)
Smiles
FC (F) (F) c1ccc (\C=C\c2nc (COc3ccc (CCCCn4ccnn4) cc3) co2) cc1
Molecular Formula
C25H23F3N4O2
Molecular Weight
468.47
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
FM32802-01Mubritinib
A10612-50Mubritinib 50mg
A10612-10Mubritinib 10mg
A10612-200Mubritinib 200mg
A10612-25Mubritinib 25mg
B1543-25Mubritinib (TAK 165)

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