Products for Research Use Only

PD318088

CAT: 0013-GTR19171696-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19171696-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PD318088 is a non-ATP competitive, allosteric inhibitor of MEK1/2. It binds to a site adjacent to the ATP-binding pocket, allowing simultaneous occupancy with ATP. This compound is a valuable research tool for investigating the MAPK/ERK pathway in both cellular and animal models of cancer and proliferative diseases.
CAS Number
391210-00-7
Product Name Alternative
Inhibitor, MAP2K, MAPKK, MEK, MEK1, MEK2, PD 318088, PD318088, PD-318088, Mitogen-activated protein kinase kinase, inhibit
Field of Research
Signal Transduction
Purity
99.60% (May vary between batches)
Solubility
DMSO:112 mg/mL (199.61 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:14 mg/mL (24.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.13 mM)
Smiles
OCC (O) CONC (=O) c1cc (Br) c (F) c (F) c1Nc1ccc (I) cc1F
Molecular Formula
C16H13BrF3IN2O4
Molecular Weight
561.09
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products