Products for Research Use Only

SU11274

CAT: 0013-GTR19171694-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171694-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SU11274 is a potent and selective Met kinase inhibitor with an IC50 of 10 nM. It demonstrates minimal activity against related kinases such as PGDFRβ, EGFR, and Tie2. This inhibitor is widely used in cancer research for in vitro and in vivo studies investigating Met-driven tumorigenesis and metastasis.
CAS Number
658084-23-2
Product Name Alternative
CDK2, c-Met/HGFR, cMet, c-Met, cMet/HGFR, Autophagy, Apoptosis, Met, Met Kinase Inhibitor, HGFR, Flk1, FGFR1, PKI-SU 11274, PKI-SU11274, PKI-SU-11274, RON, SU11274, SU-11274, SU 11274
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.62% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.81 mM) ; Ethanol:2 mg/mL (3.52 mM) ; DMSO:48.33 mg/mL (85.07 mM)
Smiles
C (=C\1/C=2C (NC1=O) =CC=C (S (N (C) C3=CC (Cl) =CC=C3) (=O) =O) C2) \C4=C (C) C (C (=O) N5CCN (C) CC5) =C (C) N4
Molecular Formula
C28H30ClN5O4S
Molecular Weight
568.09
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
MBS578719SU11274