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Monocrotaline

CAT: 0013-GTR19171636-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171636-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Monocrotaline is a macrocyclic pyrrolizidine alkaloid that inhibits organic cation transporters OCT-1 and OCT-2. It demonstrates cytotoxic effects against HepG2 liver cancer cells in vitro and is widely utilized to establish rodent models of pulmonary arterial hypertension for in vivo research.
CAS Number
315-22-0
Product Name Alternative
Crotaline; MCT; NSC28693
Field of Research
Cell Biology, Neuroscience
Purity
>98%
Bioactivity
Induces pulmonary fibrosis in animal models
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml with warming), in Ethanol (up to 10 mg/ml with warming) or in organic solvents such as Chloroform (up to 50 mg/ml)
Smiles
O=C1O[C@]2 ([C@@]3 (N (CC2) CC=C3COC (=O) [C@] (C) (O) [C@] (C) (O) [C@H]1C) [H]) [H]
Molecular Formula
C16H23NO6
Molecular Weight
325.36
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(3R,4R,5R) -4,5,8,10,12,13,13aR,13bR-octahydro-4,5-dihydroxy-3,4,5-trimethyl-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6 (3H) -dione

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