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5-Hydroxy-1-methylhydantoin

CAT: 0013-GTR19171606-04Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171606-04Size:25 mg
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Description
5-Hydroxy-1-methylhydantoin (HD-003) is a creatinine-derived antioxidant and hydroxyl radical scavenger studied for renal and vascular protection. Research indicates it suppresses high glucose-induced B2KR expression and attenuates bradykinin-driven MAPK/CTGF signaling in VSMCs, demonstrating potential in models of diabetic nephropathy and vascular remodeling.
CAS Number
84210-26-4
Product Name Alternative
5 Hydroxy 1 methylhydantoin, 5Hydroxy1methylhydantoin, 5-Hydroxy-1-methylhydantoin, Bradykinin Receptor, BradykininReceptor, bradykinin B2, HD 003, HD003, HD-003, NZ 419, NZ419, NZ-419
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.50% (May vary between batches)
Solubility
DMSO:60 mg/mL (461.18 mM)
Smiles
OC1N (C) C (=O) NC1=O
Molecular Formula
C4H6N2O3
Molecular Weight
130.1
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

5-Hydroxy-1-methylhydantoin

structure given in first source

CAS Number84210-26-4
PubChem CID3036247
IUPAC Name5-hydroxy-1-methylimidazolidine-2,4-dione
Molecular FormulaC4H6N2O3
Molecular Weight130.10
XLogP-1.4
Topological Polar Surface Area69.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Heavy Atom Count9
Formal Charge0
Complexity167
SMILES
CN1C(C(=O)NC1=O)O
InChI
InChI=1S/C4H6N2O3/c1-6-3(8)2(7)5-4(6)9/h3,8H,1H3,(H,5,7,9)
InChIKey
UPSFNXFLBMJUQW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-Hydroxy-1-methylhydantoin
CAS: 84210-26-4
CID: 3036247
Formula: C4H6N2O3
MW: 130.10
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight130.10
XLogP3-1.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass130.03784206
Monoisotopic Mass130.03784206
Topological Polar Surface Area69.6 Ų
Heavy Atom Count9
Formal Charge0
Complexity167
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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