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Bardoxolone

CAT: 0013-GTR19171757-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171757-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bardoxolone methyl is a potent synthetic triterpenoid that activates the Nrf2 pathway and inhibits NF-κB signaling, leading to antioxidant and anti-inflammatory effects. It has been investigated in vitro for cancer research by inducing apoptosis and in vivo for conditions like chronic kidney disease and pulmonary arterial hypertension.
CAS Number
218600-44-3
Product Name Alternative
Bardoxolone, CDDO, Nrf2, Inhibitor, Keap1-Nrf2, inhibit, RTA 401, RTA401, RTA-401
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology
Purity
97.90% (May vary between batches)
Solubility
DMSO:16 mg/mL (32.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.14 mM)
Smiles
CC1 (C) CC[C@@]2 (CC[C@]3 (C) [C@@H] ([C@H]2C1) C (=O) C=C1[C@@]2 (C) C=C (C#N) C (=O) C (C) (C) C2CC[C@@]31C) C (O) =O
Molecular Formula
C31H41NO4
Molecular Weight
491.66
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
FLB29884-01Bardoxolone
C13177-01Bardoxolone Methyl
S6647-25mgBardoxolone (CDDO)

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