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CUDC-101

CAT: 0013-GTR19171453-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171453-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CUDC-101 is a multi-targeted small molecule inhibitor with potent activity against HDAC, EGFR, and HER2, exhibiting IC50 values of 4.4 nM, 2.4 nM, and 15.7 nM, respectively. It has been investigated in preclinical cancer research for its potential to overcome resistance and has shown efficacy in both cellular and animal models of various solid tumors.
CAS Number
1012054-59-9
Product Name Alternative
CUDC 101, CUDC101, CUDC-101, HDAC1, HDAC3, HDAC2, HDAC4, HDAC10, HDAC8, HDAC5, HDAC, HDAC7, HDAC9, HDAC6, HER2, HER1, Histone deacetylases, Epidermal growth factor receptor, ErbB-1, EGFR, Inhibitor, inhibit
Field of Research
Epigenetics & Chromatin
Purity
>98%
Bioactivity
Dual HDAC and EGFR inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
N (C=1C2=C (C=C (OC) C (OCCCCCCC (NO) =O) =C2) N=CN1) C3=CC (C#C) =CC=C3
Molecular Formula
C24H26N4O4
Molecular Weight
434.49
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
7- ((4- ((3-Ethynylphenyl) amino) -7-methoxyquinazolin-6-yl) oxy) -N-hydroxyheptanamide

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