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NU2058

CAT: 0013-GTR19171361-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171361-01Size:10 mg
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Description
NU2058 is a guanine-derived small molecule that functions as a cyclin-dependent kinase (CDK) inhibitor and suppresses DNA topoisomerase II ATPase activity. It is utilized in cancer research for investigating cell cycle arrest and DNA damage mechanisms in both cellular and biochemical assays.
CAS Number
161058-83-9
Product Name Alternative
Inhibitor, guanine-based, O6- (Cyclohexylmethyl) guanine, O (6) -Cyclohexylmethylguanine, NU 2058, NU2058, NU-2058, inhibit, anti-cancer, ATP, Cyclin dependent kinase, CDK1, CDK2, CDK, competitive, Topo II
Field of Research
Cell Biology, Molecular Biology
Purity
98.43% (May vary between batches)
Solubility
DMSO:60 mg/mL (242.62 mM)
Smiles
Nc1nc (OCC2CCCCC2) c2nc[nH]c2n1
Molecular Formula
C12H17N5O
Molecular Weight
247.3
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

NU-2058

structure in first source

CAS Number161058-83-9
PubChem CID4564
IUPAC Name6-(cyclohexylmethoxy)-7H-purin-2-amine
Molecular FormulaC12H17N5O
Molecular Weight247.30
XLogP2.1
Topological Polar Surface Area89.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count18
Formal Charge0
Complexity271
SMILES
C1CCC(CC1)COC2=NC(=NC3=C2NC=N3)N
InChI
InChI=1S/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H3,13,14,15,16,17)
InChIKey
MWGXGTJJAOZBNW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of NU-2058
CAS: 161058-83-9
CID: 4564
Formula: C12H17N5O
MW: 247.30
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight247.30
XLogP32.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass247.14331018
Monoisotopic Mass247.14331018
Topological Polar Surface Area89.7 Ų
Heavy Atom Count18
Formal Charge0
Complexity271
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BUP13337-01NU2058
A15767-50NU2058 50mg
A15767-100NU2058 100mg
A15767-25NU2058 25mg
A15767-10NU2058 10mg
A15767-200NU2058 200mg
A15767-5NU2058 5mg
A15767-10mM-DNU2058 10mM * 1mL in DMSO

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