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A-740003

CAT: 0013-GTR19170978-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170978-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A-740003 is a potent and selective P2X7 receptor antagonist with IC50 values of 18 nM (rat) and 40 nM (human) . It has demonstrated efficacy in reducing pain in rodent models of neuropathic and inflammatory pain and has also been shown to inhibit neuroblastoma tumor growth in vivo.
CAS Number
861393-28-4
Product Name Alternative
A740003, A-740003, A 740003, inhibit, Inhibitor, P2X Receptor, P2X7 (Human), P2XRs, P2XReceptor, rat P2X7
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
96.53% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.11 mM) ; DMSO:9.5 mg/mL (20.02 mM)
Smiles
COc1ccc (CC (=O) NC (N\C (Nc2cccc3ncccc23) =N\C#N) C (C) (C) C) cc1OC
Molecular Formula
C26H30N6O3
Molecular Weight
474.55
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
S0826-5mgA-740003
sc-291774A 740003
A11316-100A 740003 100mg
A11316-50A 740003 50mg
A11316-25A 740003 25mg
A11316-10A 740003 10mg
A11316-5A 740003 5mg
217137A740003 (N- (1-{[ (cyanoimino) (5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl) -2- (3,4-dimethoxyphenyl) acetamide, A 740003, P2X7 Purinegic Receptor, A740003, A740003)

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