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Niaprazine

CAT: 0013-GTR19170970-03Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170970-03Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Niaprazine is a potent sedating antihistamine that acts as a selective H1-receptor antagonist. It is utilized in pharmacological research to study histamine-mediated pathways and has been applied in experimental models investigating sleep and sedation.
CAS Number
27367-90-4
Product Name Alternative
Disorders, autistic, AdrenergicReceptor, Adrenergic Receptor, 5HT Receptor, 5-HT2, 5-HIAA, 5HTReceptor, H1 receptor, H1-receptor, Inhibitor, Histamine Receptor, HistamineReceptor, sedative, Niaprazine, inhibit, sleep, α1-adrenergic receptor
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
99.50% (May vary between batches)
Solubility
DMSO:100 mg/mL (280.55 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.81 mM)
Smiles
CC (CCN1CCN (CC1) c1ccc (F) cc1) NC (=O) c1cccnc1
Molecular Formula
C20H25FN4O
Molecular Weight
356.44
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Niaprazine

Niaprazine is a member of piperazines.

CAS Number27367-90-4
PubChem CID71919
IUPAC NameN-[4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl]pyridine-3-carboxamide
Molecular FormulaC20H25FN4O
Molecular Weight356.4
XLogP2.6
Topological Polar Surface Area48.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count26
Formal Charge0
Complexity434
SMILES
CC(CCN1CCN(CC1)C2=CC=C(C=C2)F)NC(=O)C3=CN=CC=C3
InChI
InChI=1S/C20H25FN4O/c1-16(23-20(26)17-3-2-9-22-15-17)8-10-24-11-13-25(14-12-24)19-6-4-18(21)5-7-19/h2-7,9,15-16H,8,10-14H2,1H3,(H,23,26)
InChIKey
RSKQGBFMNPDPLR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Niaprazine
CAS: 27367-90-4
CID: 71919
Formula: C20H25FN4O
MW: 356.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight356.4
XLogP32.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass356.20123960
Monoisotopic Mass356.20123960
Topological Polar Surface Area48.5 Ų
Heavy Atom Count26
Formal Charge0
Complexity434
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
FN104313-01Niaprazine
HY-105542R-01Niaprazine (Standard)

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